1-calculate the number of disintegrations occurring in all segments of the GI tract after intake of 777KBq of a radionuclide with a10 hour physical half-life, if the f1 value is 0.75.

2-a diagnostic scan with I-123 involves administration of 15 mCi of activity to a subject.if 15% of the activity goes to liver and is retained there with a biological half-time of 24 hours and 35%of the activity goes to spleen and is retained there with a biological half-time of 10 hours, calculate the total dose to liver, spleen, red marrow, and ovaries, from the liver and spleen contributions. Use the attached MIRD S values for the reference Adult.

3- Calculate the time integral of activity for a 50 MBq source of F-18 in an organ for the following biological half time. Express your results in micro Ci, MBq-s, and number of disintegrations.

a-Tb=1 hr

b- Tb= 5hr

c- Tb =80hr

d- Tb =infinity

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