Population Genetics and Human Evolution

Complete the following discussions:

The Hardy-Weinberg equilibrium states that allele frequencies remain constant across generations unless certain influences are introduced, such as nonrandom matings or mutations.

  • Describe the Hardy-Weinberg principle.
  • Are there influences that deviate from the principle? If so, what are they? If no, why?

Deoxyribonucleic acid (DNA) profiling is a tool used in forensic investigation and paternity testing. This technique is often used by forensic scientists to identify individuals on the basis of their DNA profiles.

  • How is DNA profiling performed?
  • What are some of the novel uses of DNA profiling, other than those described in your textbook?

Sickle-cell disease is an example of balanced polymorphism as carriers of this disease are protected against malaria.

  • Describe an example of balanced polymorphism, other than sickle-cell disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, phenylketonuria (PKU), prior protein mutation, cystic fibrosis (CF), and Smith-Lemli-Opitz syndrome (SLOS).

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